Anti-CNPS (3E5)

Anti-CNPS [3E5], Recombinant, IgG3 kappa, Mouse

CloneID: 3E5

Antigen Long Description: A covalent serotype A Glucuronoxylomannan (GXM) -tetanus toxoid conjugate (GXM-TT).

Origin Pub PMID: 23911417

Buffer Composition: PBS only.

Specificity Statement: Specifically binds to CNPS.

Application Notes (Clone): This antibody binds to Glucuronoxylomannan (GXM), which is the main constituent of the C. neoformans capsule and modulates the inflammatory response of monocytes. In a later study conducted by Yuan et al. 1998 (PMID: 9488395), it was shown that switching the original murine IgG3 antibody to other IgG subtypes, in particular IgG2A, significantly prolonged animal survival in an infection model.

• SKU: ABAAb00354-5.0-BT
• Manufacturer: Absolute Antibody
• Manufacturer SKU: Ab00354-5.0-BT
• Package Unit: 1 mg
• Quantity Unit: STK
• Reactivity: Various species
• Clonality: Recombinant
• Application: ELISA
• Isotype: IgG3 kappa
• Host: Mouse