CloneID: OX-21
Heavy Chain modification: Fc Silent™
Antigen Long Description: C3bINA was purified from outdated human plasma, and subcutaneously injected into DBA/2 x Balb/c F1 mice.
Buffer Composition: PBS only.
Chimeric Use Statement: This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.
Uniprot Accession No.: P05156
Specificity Statement: This antibody is specific for human C3bINA, which is secreted into the serum.
Application Notes (Clone): This antibody binds C3bINA, and consequently can be used to rapidly purify enzymically-active C3bINA from human plasma using affinity chromatography (Hsiung, 1982), permitting the molecular characterisation of C3bINA. This technique has a variety of benefits, as it allows the purification of serum proteins at low concentration and the extraction of high yields and active enzymes, as well as being time-efficient.
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