CloneID: 2C4
Buffer Composition: PBS with 0.02% Proclin 300.
Chimeric Use Statement: This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format for improved compatibility with existing reagents assays and techniques.
Available Custom Conjugation Options: AP, HRP, Fluorescein, APC, PE, Biotin Type A, Biotin Type B, Streptavidin, FluoroProbes 647H, Atto488, APC/Cy7, PE/Cy7
Uniprot Accession No.: O55038
Specificity Statement: The antibody is specific for CXCL13. CXCL13 is a chemokine expressed in follicular stromal cells of lymphoid organs, macrophages in the peritoneal and pleural cavities and in myeloid dendritic cells. It has been shown to bind primarily to the G-protein coupled receptor CXCR5.
Application Notes (Clone): The specificity of the original format of the antibody was confirmed by ELISA analysis (EC50 = 0.02 nM). The binding affinity of the IgG1 fragment for recombinant purified mouse CXCL13 was measured by surface plasmon resonance (Kd= 13 pM) (US20080227704).
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