Anti-cytochrome C (R1D3)

Anti-cytochrome C [R1D3], Recombinant, IgG1 kappa, Mouse

CloneID: R1D3

Origin Pub PMID: 36378644

Buffer Composition: PBS with 0.02% Proclin 300.

Available Custom Conjugation Options: AP, HRP, Fluorescein, APC, PE, Biotin Type A, Biotin Type B, Streptavidin, FluoroProbes 647H, Atto488, APC/Cy7, PE/Cy7

Uniprot Accession No.: P62897

Specificity Statement: The antibody is specific for cytochrome c. The antibody binds to a variety of oxidatively modified cyt c species, such as nitrated at Tyr74 or oxidized at Met80, which lose the sixth heme ligation (Fe-Met80); it does not bind to several cyt c phospho- and acetyl-mimetics.

Application Notes (Clone): The antibody was employed to identify alternative conformations of cyt c in cells under oxidant- or senescence-induced challenge as confirmed by immunocytochemistry (Tomasina et al., 2022; PMID: 36378644).

• SKU: ABAAb03812-1.1
• Manufacturer: Absolute Antibody
• Manufacturer SKU: Ab03812-1.1
• Package Unit: 100 μg
• Quantity Unit: STK
• Reactivity: Mouse (Murine)
• Clonality: Recombinant
• Application: Immunocytochemistry
• Isotype: IgG1 kappa
• Host: Mouse