CloneID: RKSE60
Antigen Long Description: The original antibody was generated by immunizing a BALB/c mouse with Cytokeratins from the Human epidermis.
Buffer Composition: PBS with 0.02% Proclin 300.
Available Custom Conjugation Options: AP, HRP, Fluorescein, APC, PE, Biotin Type A, Biotin Type B, Streptavidin, FluoroProbes 647H, Atto488, APC/Cy7, PE/Cy7
Uniprot Accession No.: P13645
Specificity Statement: The original antibody reacts exclusively with Cytokeratin 10 which is present in Keratinizing stratified epithelia and in differentiated areas of highly differentiated squamous cell carcinomas.
Application Notes (Clone): The original antibody specifically reacted with keratinizing stratified epithelia and squamous cell carcinomas derived from these by IHC (Ramaekers et al. 1983; PMID: 6350235). The antibody stained cytokeratin 10 from cultured human keratinocytes by immunohistochemistry (Muijen et al, 1987; PMID: 2442018). This antibody was used for detection of cytokeratin 10 in psoriatic skin and normal skin by flow cytometry (van Erp et al., 1989; PMID: 2479273). The antibody detected cytokeratin 10 from human foreskin keratin preparation, by western blot analysis (Ramaekers et al., 1990; PMID: 1690512).
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