CloneID: A53-B/A2
Heavy Chain modification: Fc Silent™
Antigen Long Description: The original antibody was generated by immunizing a mouse with live MCF-7 cells.
Buffer Composition: PBS with 0.02% Proclin 300.
Chimeric Use Statement: This is a reformatted mouse IgG2a Fc Silent™ antibody, based on the original mouse IgG2a format, created for improved compatibility with existing reagents, assays and techniques.
Available Custom Conjugation Options: AP, HRP, Fluorescein, APC, PE, Biotin Type A, Biotin Type B, Streptavidin, FluoroProbes 647H, Atto488, APC/Cy7, PE/Cy7
Uniprot Accession No.: P08727
Specificity Statement: This antibody is specific for cytokeratin type 19.
Application Notes (Clone): The original version of this antibody was used for flow cytometry on cells from transbronchial lung biopsy tissues (Song et al., 2018; PMID:29721074). The original version of this antibody was also used for immunohistochemistry on normal tissues distant from tumours (Bártek et al., 1986; PMID:2433255), on a wide variety of normal human tissue (Kasper et al., 1987; PMID:2450753), and on carcinomas of the skin (Tazawa et al., 1990), and on lesional and non lesional psoriatic skin. (Wollina and Karsten., 1988; PMID:2466444). This antibody was used for immunofluorescence on human mammary carcinoma and the epithelial (Karsten et al., 1985; PMID:2410280).
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