CloneID: 7A1
Antigen Long Description: The original antibody was isolated from a combinatorial phage display library generated from a mite allergic patient.
Buffer Composition: PBS with 0.02% Proclin 300.
Available Custom Conjugation Options: AP, HRP, Fluorescein, APC, PE, Biotin Type A, Biotin Type B, Streptavidin, FluoroProbes 647H, Atto488, APC/Cy7, PE/Cy7
Uniprot Accession No.: P49278
Specificity Statement: This antibody binds to an epitope on the Der p 2 which overlaps with the human IgE binding sites. The antibody recognized the six variants: Der p 2.0101, Der p 2.0102, Der p 2.0103, Der f 2.0101, Der f 2.0102, and Der f 2.0103.
Application Notes (Clone): The crystal structure of Der p 2.0103–7A1Fab was determined. The specificity of the original format of the antibody was confirmed by ELISA analysis. The antibody was able to inhibit Der p 2.0103 (Glesner et al., 2019; PMID: 31554696).
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