Anti-DR5 (Fab-BDF1)

Anti-DR5 [Fab-BDF1], Recombinant, IgG1 kappa, Mouse

CloneID: Fab-BDF1

Antigen Long Description: Human immobilized DR5.

Buffer Composition: PBS only.

Chimeric Use Statement: This chimeric mouse antibody was made using the variable domain sequences of the original human Fab format, for improved compatibility with existing reagents, assays and techniques.

Uniprot Accession No.: Q9BY82

Specificity Statement: The antibody binds to human DR5 with nanomolar affinity. The original format of this antibody has an IC50-value of 2 nM.

Application Notes (Clone): The antibody binds to human DR5, a receptor that can be activated by tumor necrosis factor-related ligands and transduces apotposis signals. The antibody occludes the smaller of the two Apo2L/TRAIL binding sites on DR5

• SKU: ABAAb00427-1.1-BT
• Manufacturer: Absolute Antibody
• Manufacturer SKU: Ab00427-1.1-BT
• Package Unit: 1 mg
• Quantity Unit: STK
• Reactivity: Human
• Clonality: Recombinant
• Application: ELISA, Blocking
• Isotype: IgG1 kappa
• Host: Mouse