CloneID: 133D7-1
Heavy Chain modification: Fc Silent™
Antigen Long Description: The original antibody was raised by immunizing a rabbit with dystrophin.
Buffer Composition: PBS with 0.02% Proclin 300.
Chimeric Use Statement: This is a reformatted human IgG1 Fc Silent™ antibody, based on the original human IgG format, created for improved compatibility with existing reagents, assays and techniques.
Available Custom Conjugation Options: AP, HRP, Fluorescein, APC, PE, Biotin Type A, Biotin Type B, Streptavidin, FluoroProbes 647H, Atto488, APC/Cy7, PE/Cy7
Uniprot Accession No.: P11532
Specificity Statement: This antibody is specific for the LLQVAVEDR peptide from dystrophin.
Application Notes (Clone): The original antibody was used for LBA/LCMS on beagle skeletal muscle and human skeletal muscle to quantify dystrophin. The binding affinity of this antibody was assessed using an MSD assay on the LLQ peptide it showed good affinity for its peptide (WO2023064947A1).
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