Anti-Envelope glycoprotein H; Envelope glycoprotein L (Fab-RC)

Anti-Envelope glycoprotein H; Envelope glycoprotein L [Fab-RC], Recombinant, IgG1 kappa, Human

CloneID: Fab-RC

Antigen Long Description: The original antibody was raised from the white blood cells of a human individual immunized with zoster vaccine.

Buffer Composition: PBS only.

Uniprot Accession No.: Q775J3; Q9J3N1

Specificity Statement: This antibody is specific for the combination of gH and gL and does not detect the proteins in isolation.

Application Notes (Clone): The original antibody was used for surface plasmon resonance on VZV gHgL. This antibody was used for a neutralization assay. Here is showed it was able to inhibit gB/gHgL-mediated membrane fusion. The structure of this antibody was determined using x-ray crystallography (Xing et al., 2015; PMID:25918416). This antibody was used for immunohistochemistry on fixed and unfixed VZV-infected and control HFL cells. This antibody was also used for a plaque reduction assay on VZV-infected HFL cells. Further this antibody was used for immunoprecipitation on VZV-infected and uninfected HFL cells (Birlea et al., 2013; PMID:23077312).

• SKU: ABAAb04452-10.0-BT
• Manufacturer: Absolute Antibody
• Manufacturer SKU: Ab04452-10.0-BT
• Package Unit: 1 mg
• Quantity Unit: STK
• Reactivity: Virus
• Clonality: Recombinant
• Application: Immunoprecipitation, Immunohistochemistry, Neutralization, Super-Resolution Microscopy, Crystallography
• Isotype: IgG1 kappa
• Host: Human