CloneID: JAR5
Heavy Chain modification: Fc Silent™
Antigen Long Description: Genome-derived neisserial Antigen 1870.
Origin Pub PMID: 26106082
Buffer Composition: PBS only.
Chimeric Use Statement: This is a reformatted mouse IgG2b Fc Silent™ antibody, based on the original mouse IgG2b format, created for improved compatibility with existing reagents, assays and techniques.
Uniprot Accession No.: C6KHT4
Specificity Statement: This antibody binds to FHbp with a Kd of 54 pM.
Application Notes (Clone): This antibody binds to N. meningitidis FHbp, a virulence factor critical for surviving of the bacteria in the human host. This antibody shows strong inhibition of human FH binding.