CloneID: mAb4F5
Antigen Long Description: The original antibody was generated by immunizing mice with FVIIaDVQ.
Buffer Composition: PBS with 0.02% Proclin 300.
Available Custom Conjugation Options: AP, HRP, Fluorescein, APC, PE, Biotin Type A, Biotin Type B, Streptavidin, FluoroProbes 647H, Atto488, APC/Cy7, PE/Cy7
Uniprot Accession No.: P08709
Specificity Statement: The antibody is specific for FVIIa. In particular, the epitope interacts with the periphery of the hydrophobic pocket.
Application Notes (Clone): The binding affinity of original format of the antibody to FVIIaDVQ was measured by surface plasmon resonance (Kd= 32 pM). The crystal structure of the Fab fragment of the antibody was determined (Jiang et al., 2019; PMID: 31294329).