CloneID: Nb7
Antigen Long Description: The original antibody was raised by using a nanobody yeast display library from immunized alpaca peripheral blood lymphocyte mRNA, and the US28/CX3CL1 complex was used to select the highest affinity binders
Buffer Composition: PBS only.
Chimeric Use Statement: This is a chimeric antibody, developed from the original camelid VHH antibody, specifically engineered for enhanced compatibility with existing reagents, assays, and techniques.
Uniprot Accession No.: P69332; P69333
Specificity Statement: This antibody is specific for the intracellular surface of US28.
Application Notes (Clone): The crystal structure of the original antibody was determined (Burg et al., 2015; PMID:25745166). This antibody was used for an ELISA on US28 protein. Further this antibody showed the ability to increase the binding of CX3CL1 to US28 (De Groof et al., 2019; PMID:31244224).
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