Anti-Genome polyprotein (14B10)

Anti-Genome polyprotein [14B10], Recombinant, IgG1 kappa, Human

CloneID: 14B10

Heavy Chain modification: Fc Silent™

Antigen Long Description: The original antibody was raised by immunizing a mouse with CVA16.

Buffer Composition: PBS only.

Chimeric Use Statement: This is a reformatted human IgG1 Fc Silent™ antibody, based on the original human IgG1 format, created for improved compatibility with existing reagents, assays and techniques.

Uniprot Accession No.: Q9QF31

Specificity Statement: This antibody is specific for the threefold plateau of the canyon of CVA16.

Application Notes (Clone): The original antibody was used for a neutralization assay against CVA16 in human rhabdomyosarcoma. Further an ELISA was performed on 16 strains of CVA16. The structure of this antibody was determined using cryo-EM (He et al., 2020; PMID:32027857).

• SKU: ABAAb04404-10.3-BT
• Manufacturer: Absolute Antibody
• Manufacturer SKU: Ab04404-10.3-BT
• Package Unit: 1 mg
• Quantity Unit: STK
• Reactivity: Virus
• Clonality: Recombinant
• Application: ELISA, Neutralization
• Isotype: IgG1 kappa
• Host: Human