CloneID: VHH 17B
Antigen Long Description: The original antibody was raised by immunizing a dromedary with poliovirus type 1 Sabin strain.
Buffer Composition: PBS only.
Chimeric Use Statement: This is a chimeric antibody, developed from the original camelid VHH antibody, specifically engineered for enhanced compatibility with existing reagents, assays, and techniques.
Uniprot Accession No.: P03300
Specificity Statement: This antibody is specific for the top of the VP3 protein from the genome polyprotein of the poliovirus.
Application Notes (Clone): The structure of the original antibody was determined using cryo-EM (Strauss et al., 2017; PMID:27852863). The binding strength of the original antibody to poliovirus antigens was determined using surface plasmon resonance (Thys et al., 2011; PMID:21371506).