Anti-Glucose-dependent insulinotropic Receptor (Gipg013)

Anti-Glucose-dependent insulinotropic Receptor [Gipg013], Recombinant, IgG lambda, Rabbit
SKU
ABAAb00424-23.0
Packaging Unit
200 μg
Manufacturer
Absolute Antibody

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CloneID: Gipg013

Antigen Long Description: Human GIPr.

Buffer Composition: PBS with 0.02% Proclin 300.

Chimeric Use Statement: This full-length, chimeric rabbit antibody was made using the variable domain sequences of the original Mouse scFv format, for improved compatibility with existing reagents, assays and techniques.

Available Custom Conjugation Options: AP, HRP, Fluorescein, APC, PE, Biotin Type A, Biotin Type B, Streptavidin, FluoroProbes 647H, Atto488, APC/Cy7, PE/Cy7

Uniprot Accession No.: Q8TDV5

Specificity Statement: The original has a Ki value of 7 nM and a Kd value of 6.8 nM for human GIPr.

Application Notes (Clone): This antibody binds to GIPr, a GPCR expressed on pancreatic beta-cells, where activation leads to the release of insulin. Endogeonous ligands for the receptor include oleylethanolamide and lysophosphatidylcholine. The antibody acts as a competitive antagonist. In rat islets, the antibody inhibits GIP-induced secretion of insulin by up to 81%.
More Information
SKU ABAAb00424-23.0
Manufacturer Absolute Antibody
Manufacturer SKU Ab00424-23.0
Package Unit 200 μg
Quantity Unit STK
Reactivity Human, Mouse (Murine), Rat (Rattus), Dog (Canine)
Clonality Recombinant
Application Immunofluorescence, ELISA, Blocking
Isotype IgG lambda
Host Rabbit
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