CloneID: R1
Heavy Chain modification: ScFv
Antigen Long Description: The original antibody was generated by immunizing two New Zealand white rabbits with recombinant gp350 protein. A phage-displayed antibody library was constructed, and the antibody was isolated by panning against gp350.
Buffer Composition: PBS only.
Chimeric Use Statement: This is a reformatted human scFv antibody, based on the original human scFv format, created for improved compatibility with existing reagents, assays and techniques.
Uniprot Accession No.: P03200
Specificity Statement: The antibody binds specifically gp350 protein of EBV.
Application Notes (Clone): The specificity of the antibody was confirmed by sandwich ELISA analysis. The antibody could block the binding activity of gp350 and CR2, as is shown by ELISA analysis. The antibody could dose-dependently block the combination of gp350 and CR2 expressed in cell line G4, as is shown by flow cytometry. Further, the antibody could block Epstein-Barr virus particles from infecting CR2 positive cells (CN114409766A).
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