Antigen Long Description: A phage immune library generated from a long-term non-progressors with HIV neutralizing antibodies in his plasma. The phage library was screened on recombinant soluble gp140 envelope (Env) proteins and the antibody was isolated.
Buffer Composition: PBS only.
Specificity Statement: The antibody is specific for gp41. It recognizes an epitope localized in the pocket binding domain of the C heptad repeat (CHR) in the ectodomain of gp41, but only in the trimeric context.
Application Notes (Clone): The specificity of the original format of the antibody was confirmed by ELISA analysis (Trott et al., 2014; PMID:24828352).