Anti-gp41 (A7)

Anti-gp41 [A7], Recombinant, IgG lambda, Rabbit

CloneID: A7

Antigen Long Description: A phage immune library generated from a long-term non-progressors with HIV neutralizing antibodies in his plasma. The phage library was screened on recombinant soluble gp140 envelope (Env) proteins and the antibody was isolated.

Buffer Composition: PBS only.

Chimeric Use Statement: This full-length chimeric rabbit antibody was made using the variable domain sequences of the original Human scFv format for improved compatibility with existing reagents assays and techniques.

Specificity Statement: The antibody is specific for gp41, and it binds to structural elements of the third variable loop V3.

Application Notes (Clone): The specificity of the original format of the antibody was confirmed by ELISA analysis. The antibody showed neutralizing activity against a panel of standardized Tier 1 and Tier 2 HIV-1 pseudo virions on Tzm-bl cells (Trott et al., 2014; PMID:24828352).

• SKU: ABAAb03525-23.0-BT
• Manufacturer: Absolute Antibody
• Manufacturer SKU: Ab03525-23.0-BT
• Package Unit: 1 mg
• Quantity Unit: STK
• Reactivity: Various species
• Clonality: Recombinant
• Application: ELISA
• Isotype: IgG lambda
• Host: Rabbit