Antigen Long Description: A phage immune library generated from a long-term non-progressors with HIV neutralizing antibodies in his plasma. The phage library was screened on recombinant soluble gp140 envelope (Env) proteins and the antibody was isolated.
Buffer Composition: PBS only.
Specificity Statement: The antibody is specific for gp41, and it binds to structural elements of the third variable loop V3.
Application Notes (Clone): The specificity of the original format of the antibody was confirmed by ELISA analysis. The antibody showed neutralizing activity against a panel of standardized Tier 1 and Tier 2 HIV-1 pseudo virions on Tzm-bl cells (Trott et al., 2014; PMID:24828352).