Anti-GXM (2E9)

Anti-GXM [2E9], Recombinant, IgG1 lambda, Human

CloneID: 2E9

Antigen Long Description: The original antibody was generated from the peripheral blood lymphocytes of glucuronoxylomannan-tetanus toxoid conjugate (GXM-TT)-immunized individual.

Origin Pub PMID: 7622223

Buffer Composition: PBS only.

Chimeric Use Statement: This reformatted human antibody was made using the variable domain sequences of the original Human IgM format for improved compatibility with existing reagents assays and techniques.

Specificity Statement: This antibody is specific for GXM or glucuronoxylomannan from Cryptococcus neoformans. GXM is a polysaccharide expressed on the surface of C. neoformans. This antibody binds an epitope of C. neoformans that is different from the epitope of another anti-GXM antibody 2H1.

Application Notes (Clone): This antibody was used for the immunofluorescent labelling of C. neoformans serotype D and A. This antibody can be used in combination with another anti-GXM antibody 2H1 for detection of all four serotypes of C. neoformans GXM using sandwich ELISA. The antibody 2H1 is used as capture antibody and 2E9 is used as a detection antibody (PMID: 7622223).

• SKU: ABAAb03489-10.0-BT
• Manufacturer: Absolute Antibody
• Manufacturer SKU: Ab03489-10.0-BT
• Package Unit: 1 mg
• Quantity Unit: STK
• Reactivity: Various species
• Clonality: Recombinant
• Application: Immunofluorescence, ELISA
• Isotype: IgG1 lambda
• Host: Human