Anti-HER2/neu (SER4)

Anti-HER2/neu [SER4], Recombinant, IgG1 kappa, Mouse

CloneID: SER4

Heavy Chain modification: Fc Silent™

Antigen Long Description: Recombinant HER2/neu.

Buffer Composition: PBS only.

Uniprot Accession No.: P04626

Specificity Statement: The antibody binds specifically to the extracellular domain of human ErbB-2.

Application Notes (Clone): The antibody binds to human ErbB-2, a receptor tyrosine kinase (RTK) controlling cell growth and microtubule stabilization. Full-length antibody or Fab fragments cross-linked by secondary antibody had a growth-inhibiting effect onf ErbB-2 positive MDA-MB-453 cells. This effect was not seen with Fab fragments alone.

• SKU: ABAAb00383-1.4-BT
• Manufacturer: Absolute Antibody
• Manufacturer SKU: Ab00383-1.4-BT
• Package Unit: 1 mg
• Quantity Unit: STK
• Reactivity: Human
• Clonality: Recombinant
• Application: ELISA
• Isotype: IgG1 kappa
• Host: Mouse