Anti-HIV p24 antibody; HIV gp120 antibody (1F7)

Anti-HIV p24 antibody; HIV gp120 antibody [1F7], Recombinant, IgG kappa, Rabbit

CloneID: 1F7

Antigen Long Description: The original antibody was generated by immunizing BALB/c mice with pooled human polyclonal HIVIG.

Buffer Composition: PBS only.

Specificity Statement: The anti-idiotypic antibody recognizes antibodies that react to different components of the HIV virus, such as gp120, p24. The antibody does not react with antibodies derived from SLE and B cell lymphoma.

Application Notes (Clone): The HIV-1 antigen capture ELISA was used to test the binding of human monoclonal anti-HIV-1 to the antibody. The antibody bound to anti-p24 antibodies and anti-gp120 antibodies. Western blot analysis confirmed that the antibody reacts with human antibodies of different HIV-1 antigen specificities (Wang et al., 1992; PMID: 1378015). SHIV-infected macaques were immunized with the antibody. Significant increases in breadth and potency of HIV-1 neutralizing antibody titers to one or more virus strains were detected in all three of the 1F7 immunized macaques (US6057421A).

• SKU: ABAAb03855-23.0-BT
• Manufacturer: Absolute Antibody
• Manufacturer SKU: Ab03855-23.0-BT
• Package Unit: 1 mg
• Quantity Unit: STK
• Reactivity: Human
• Clonality: Recombinant
• Application: Western Blotting, ELISA, In Vivo Assay
• Isotype: IgG kappa
• Host: Rabbit