CloneID: ABM109.2
Antigen Long Description: The antibody is the humanized version of the parental ABM109.
Buffer Composition: PBS with 0.02% Proclin 300.
Available Custom Conjugation Options: AP, HRP, Fluorescein, APC, PE, Biotin Type A, Biotin Type B, Streptavidin, FluoroProbes 647H, Atto488, APC/Cy7, PE/Cy7
Uniprot Accession No.: Q9H293
Specificity Statement: The antibody is specific for human, mouse and simian IL-25. IL-25 is a cytokine that belongs to the IL-17 cytokine family and is secreted by type 2 helper T cells and mast cells. IL-25 induces the production of other cytokines, including IL-4, IL-5 and IL-13, in multiple tissues and stimulates the expansion of eosinophils.
Application Notes (Clone): The original antibody could neutralize recombinant human IL-25 activity in HT-29 cells; the affinity of the antibody for IL-25 were measured using Surface Plasma Resonance (Kd = 24 pM).
English
Deutsch
