Anti-IL-4 (OX-81)

Anti-IL-4 [OX-81], Recombinant, IgG2b kappa, Rat

CloneID: OX-81

Heavy Chain modification: Fc Silent™

Antigen Long Description: OX-81 was prepared by immunizing BALB/c mice with full-length IL-4.

Buffer Composition: PBS only.

Chimeric Use Statement: This chimeric rat antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.

Uniprot Accession No.: P20096

Specificity Statement: OX-81 binds specifically to IL-4. IL-4 is a globular signalling protein which is involved in the stimilation of activated B and T cell proliferation and the differentiation of B cells into plasma cells. IL-4 also regulates B cell class switching to IgE, upregulates MHC class II expression and plays a role in the inflammation response and wound repair.

Application Notes (Clone): OX-81 can be used to neutralise the effects produced by IL-4 and for FC studies.

• SKU: ABAAb00556-8.4-BT
• Manufacturer: Absolute Antibody
• Manufacturer SKU: Ab00556-8.4-BT
• Package Unit: 1 mg
• Quantity Unit: STK
• Reactivity: Rat (Rattus)
• Clonality: Recombinant
• Application: Flow Cytometry, Blocking
• Isotype: IgG2b kappa
• Host: Rat