Anti-Insulin-degrading Enzyme (Fab-IDE)

Anti-Insulin-degrading Enzyme [Fab-IDE], Recombinant, IgG1 kappa, Mouse

CloneID: Fab-IDE

Antigen Long Description: Human IDE.

Buffer Composition: PBS only.

Chimeric Use Statement: This full-length, reformatted mouse antibody was made using the variable domain sequences of the original Mouse scFv format, for improved compatibility with existing reagents, assays and techniques.

Uniprot Accession No.: P14735

Specificity Statement: Binds specificially to human IDE with a Kd of 3.72 nM.

Application Notes (Clone): This antibody binds human insulin degrading enzyme, which breaks down insulin as well as amyloid peptides and is suggested to play a role in both diabetes and Alzheimer's. Antibody binding does not affect steady-state kinetics of IDE.

• SKU: ABAAb00406-1.1-BT
• Manufacturer: Absolute Antibody
• Manufacturer SKU: Ab00406-1.1-BT
• Package Unit: 1 mg
• Quantity Unit: STK
• Reactivity: Human
• Clonality: Recombinant
• Application: ELISA
• Isotype: IgG1 kappa
• Host: Mouse