CloneID: A4
Antigen Long Description: Human keratin-17.
Buffer Composition: PBS with 0.02% Proclin 300.
Chimeric Use Statement: This full-length, chimeric human antibody was made using the variable domain sequences of the original Mouse scFv format, for improved compatibility with existing reagents, assays and techniques.
Available Custom Conjugation Options: AP, HRP, Fluorescein, APC, PE, Biotin Type A, Biotin Type B, Streptavidin, FluoroProbes 647H, Atto488, APC/Cy7, PE/Cy7
Uniprot Accession No.: Q04695
Specificity Statement: Binds specifically to human keratin, no observed crossreactivity.
Application Notes (Clone): This antibody binds to human keratin (K17), which is involved in the formation of skin appendages, growth of hair follicles, regulation of protein synthesis, and epithelial cell growth through SFN-binding and mTOR-stimulation.