CloneID: 24.1.2
Antigen Long Description: The original antibody was generated by immunizing BALB/c mice with streptococcal M type 5 membranes followed by a second, boosting dose of Lysin M5.
Origin Pub PMID: 11282394
Buffer Composition: PBS with 0.02% Proclin 300.
Available Custom Conjugation Options: AP, HRP, Fluorescein, APC, PE, Biotin Type A, Biotin Type B, Streptavidin, FluoroProbes 647H, Atto488, APC/Cy7, PE/Cy7
Uniprot Accession No.: P02977
Specificity Statement: This antibody reacts with α-helical molecules and is anti-nuclear (binds DNA). Specifically, it binds streptococcal M-protein (type 5), human myosin, actin, tropomyosin, and troponin.
Application Notes (Clone): This antibody binds myosin at a low relative avidity, as determined in a competitive ELISA (Mertens et al., 2000; PMID: 11282394).