Anti-M protein

Anti-M protein, Recombinant, IgG kappa, Rabbit
SKU
ABAAb03916-23.0-BT
Packaging Unit
1 mg
Manufacturer
Absolute Antibody

Availability: loading...
Price is loading...
CloneID: 36.2.2

Antigen Long Description: The original antibody was generated by immunizing BALB/c BYJ mice with streptococcal M type 5 membranes followed by a second, boosting dose of M type 5 streptococcal membranes.

Origin Pub PMID: 11282394

Buffer Composition: PBS only.

Uniprot Accession No.: P02977

Specificity Statement: This antibody reacts with α-helical molecules. Specifically, it binds streptococcal M-protein (type 5), human myosin, actin, keratin, tropomyosin, troponin, laminin, ganglioside, glycophorin M,N

Application Notes (Clone): This antibody reacts with human heart cells and whole streptococci (group A, M type 5), as shown in an ELISA, and human heart cells, human sarcolemma, and group A streptococcal membranes, as shown in a WB (Cunnigham et al., 1984; PMID: 6384047). This antibody reacts with the heavy chain of skeletal muscle myosin. Specifically, it reacts with light meromyosin fragments, as shown in WB and competitive inhibition assays (Cunningham et al., 1986; PMID: 3510006). This antibody labels the cytoplasm of epidermal cells and epidermal appendages in normal and psoriatic skin, as shown by immunofluorescent staining (Swerlick et al., 1986; PMID: 3525693). This antibody binds CV (B3), as shown in an ELISA; neutralizes PV-1 and CV (B3), as shown in a plaque-reduction neutralization assay; and is cytotoxic to rat heart cells and fibroblasts, as shown in a cytotoxicity assay (Cunningham et al., 1992; PMID: 1311095). This antibody reacts with retinal S-antigen (S-Ag), as shown in an ELISA (Lerner et al., 1995; PMID: 8722579). This antibody was found to be cytotoxic for rat heart cells (Antone et al., 1997 ;PMID: 9548482). This antibody binds myosin at a high relative avidity, as determined in a competitive ELISA. (Mertens et al., 2000; PMID: 11282394).
More Information
SKU ABAAb03916-23.0-BT
Manufacturer Absolute Antibody
Manufacturer SKU Ab03916-23.0-BT
Package Unit 1 mg
Quantity Unit STK
Reactivity Human, Rat (Rattus), Various species, Virus
Clonality Recombinant
Application Immunofluorescence, Western Blotting, ELISA, Hemagglutination Inhibition
Isotype IgG kappa
Host Rabbit
Product information (PDF) Download
MSDS (PDF) Download