Anti-Membrane type 1 metalloprotease (LEM-2/15)

Anti-Membrane type 1 metalloprotease [LEM-2/15], Recombinant, IgG1 kappa, Human

CloneID: LEM-2/15

Antigen Long Description: The cyclic peptide possessing the sequence of residues 218-233 of the V-B-loop of MT1-MMP.

Buffer Composition: PBS only.

Chimeric Use Statement: This chimeric human antibody was made using the variable domain sequences of the original mouse IgG1 format for improved compatibility with existing reagents, assays and techniques.

Specificity Statement: This antibody binds to residues 218-233 of the V-B loop of MT1-MMP with a Kd of 2.32E10-9M.

Application Notes (Clone): This antibody binds to residues 218-233 of the V-B loop of MT1-MMP which is a mediator of cell migration and is frequently involved in malignancy of tumours by promoting metastasis. The antibody acts as a non-competitive inhibitor of the receptor.

• SKU: ABAAb00364-10.0-BT
• Manufacturer: Absolute Antibody
• Manufacturer SKU: Ab00364-10.0-BT
• Package Unit: 1 mg
• Quantity Unit: STK
• Reactivity: Human
• Clonality: Recombinant
• Application: ELISA, Blocking
• Isotype: IgG1 kappa
• Host: Human