Anti-MHC II (OX-6)

Anti-MHC II [OX-6], Recombinant, IgG2a kappa, Mouse
SKU
ABAAb00543-2.0-BT
Packaging Unit
1 mg
Manufacturer
Absolute Antibody

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CloneID: OX-6

Antigen Long Description: This antibody was prepared by subcutaneously injecting non-polymorphic MHC class II (Ia-like glycoproteins) from the membranes of rat thymocytes into BALB/c mice.

Buffer Composition: PBS only.

Chimeric Use Statement: This reformatted mouse antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.

Specificity Statement: This antibody recognises a monomorphic determinant of the rat MHC II (I-A) antigen present on B lymphocytes, dendritic cells, some macrophages and certain epithelial cells. It also cross-reacts with mouse MHC, specifically I-A[k] and I-A[s]

Application Notes (Clone): This antibody binds to the rat MHC II (I-A) antigen, and cross-reacts with mouse I-A[k] and I-A[s]. Consequently, this antibody can be used to assess the tissue distribution of rat Ia antigens, indicating high Ia antigen expression on peripheral B lymphocytes, and significantly lower expression on thymocytes and T lymphocytes (McMaster, 1979).
More Information
SKU ABAAb00543-2.0-BT
Manufacturer Absolute Antibody
Manufacturer SKU Ab00543-2.0-BT
Package Unit 1 mg
Quantity Unit STK
Reactivity Mouse (Murine), Rat (Rattus)
Clonality Recombinant
Application Immunofluorescence, Immunoprecipitation, Western Blotting, Flow Cytometry, Immunohistochemistry, Radioimmunoassay (RIA), Immunocytochemistry
Isotype IgG2a kappa
Host Mouse
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