Target: CD317
Clone: 927
Specificity: Clone 927 activity is directed against murine CD317 (BST2; PDCA-1).
Purification method: This monoclonal antibody was purified using Protein G
Antigen Distribution: Murine CD317 is expressed by IFN-producing cells in naïve mouse spleen and by a wide variety of cell lines including T cells, mast cells, B cells, fibroblast cells, and pluripotent embryonal carcinoma cells. Additionally, mice challenged by influenza or other stimuli (CpG, LPS, murine CMV, poly(I:C), and imiquimod) express CD317 in DC and other myeloid cells as well as T cells, B cells, NKT cells, and some NK cells. CD317 is also expressed on CD138+ plasma cells in naïve mice and is upregulated by viral stimulation.
Immunogen: Mouse plasmacytoid dendritic cells
Concentration: ≥ 2.0 mg/ml
Formulation: Sterile, preservative-free, solution in PBS. BSA and Azide free.
Purity: >98% by SDS-PAGE and HPLC
Endotoxin: ≤ 0.5 EU/mg as determined by the LAL method
Aggregation: Aggregation level ≤ 1%
Use: Products are for research use only. Not for use in diagnostic or therapeutic procedures.
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