Target: CD64
Clone: 10,1
Specificity: Clone 10.1 recognizes an epitope on human FcγRI
Purification method: This monoclonal antibody was purified using Protein A
Antigen Distribution: FcγRI (CD64) is an IgG receptor expressed by monocytes and myeloid cell lines.
Background: Fc gamma receptors (FcγRs) are membrane-bound proteins which control and mediate communication of IgG antibodies within the immune system. These receptors play a crucial role in the link between the innate and adaptive immune system. FcγRI, CD64, is expressed on dendritic cells, macrophages/monocytes, and granulocytes. Of the FcγRs, FcγRI is capable of interacting with monomeric IgG with relatively high affinity.
Immunogen: Rheumatoid synovial fluid cells and fibronectin purified human monocytes
Concentration: >2.0 mg/ml
Formulation: This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (PBS) pH 7.2 – 7.4, 150 mM NaCl with no carrier protein, potassium or preservatives added. BSA and azide free
Purity: >98% by SDS-PAGE and HPLC
Endotoxin: ≤ 0.5 EU/mg as determined by the LAL method
Aggregation: Aggregation level ≤ 1%
Use: Products are for research use only. Not for use in diagnostic or therapeutic procedures.
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