CloneID: 13B12
Antigen Long Description: The original antibody was generated by immunizing mice with recombinant Mycobacterium tuberculosis MPT32 protein.
Buffer Composition: PBS with 0.02% Proclin 300.
Available Custom Conjugation Options: AP, HRP, Fluorescein, APC, PE, Biotin Type A, Biotin Type B, Streptavidin, FluoroProbes 647H, Atto488, APC/Cy7, PE/Cy7
Uniprot Accession No.: P9WIR7
Specificity Statement: This antibody binds the MPT32 protein of Mycobacterium tuberculosis (MTB). MPT32 is a protein encoded by the Mtb Rv1980 gene, is one of the important secretory protein of the pathogenic bacteria, which is a candidate protein for the diagnosis of MTB infections. MPT32 has high immunogenicity and serves as a potent antigen in animals immunized with live bacteria, it induces a strong delayed-type hypersensitivity (DTH) in immunized animals. It mostly elicits a Th1 type of T-cell response in healthy humans; induces IFN-gamma production from CD4+ and CD8+ cells.
Application Notes (Clone): The binding characterization of this antibody towards Mycobacterium tuberculosis MPT32 protein was done using ELISA. This antibody can also recognize MTP32 protein from tuberculosis patient samples in a western blot (CN114591427).