Anti-N-acyl homoserine lactones (RS2-1G9)

Anti-N-acyl homoserine lactones [RS2-1G9], Recombinant, IgG1 lambda, Mouse
SKU
ABAAb00343-1.4
Packaging Unit
200 μg
Manufacturer
Absolute Antibody

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CloneID: RS2-1G9

Heavy Chain modification: Fc Silent™

Antigen Long Description: The 4-methoxyphenyl amide AHL analog.

Origin Pub PMID: 17400249

Buffer Composition: PBS with 0.02% Proclin 300.

Available Custom Conjugation Options: AP, HRP, Fluorescein, APC, PE, Biotin Type A, Biotin Type B, Streptavidin, FluoroProbes 647H, Atto488, APC/Cy7, PE/Cy7

Specificity Statement: Binds 3-oxo-C12-HSL with a Kd of 150 nM

Application Notes (Clone): This antibody, originally raised in mice, binds to several homoserine lactones from P. aeruginosa. Homoserine lactones (HSL) are signalling molecules in bacteria used for quorum sensing, required for successful estabilshment of infecion. RS2-1G9 interferes with quorum sensing and was shown to protect murine bone marrow derived macrophages, from the cytotoxic P. aeruginosa quorum sensing signalling molecule N-3-oxo-dodecanoyl-homoserine lactone (PMID: 18304641).
More Information
SKU ABAAb00343-1.4
Manufacturer Absolute Antibody
Manufacturer SKU Ab00343-1.4
Package Unit 200 μg
Quantity Unit STK
Reactivity Various species
Clonality Recombinant
Application ELISA, Blocking
Isotype IgG1 lambda
Host Mouse
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