CloneID: AbAb-P-selectin
Heavy Chain modification: Fc Silent™
Antigen Long Description: The original antibody was isolated from a phage antibody library by panning against P-selectin.
Buffer Composition: PBS with 0.02% Proclin 300.
Chimeric Use Statement: This is a reformatted human IgG1 Fc Silent™ antibody, based on the original human IgG1 format, created for improved compatibility with existing reagents, assays and techniques.
Available Custom Conjugation Options: AP, HRP, Fluorescein, APC, PE, Biotin Type A, Biotin Type B, Streptavidin, FluoroProbes 647H, Atto488, APC/Cy7, PE/Cy7
Uniprot Accession No.: P16109
Specificity Statement: The antibody specifically binds to human P-selectin.
Application Notes (Clone): The specificity of the antibody was confirmed by ELISA analysis. In vivo experiments using the mouse model of rheumatoid arthritis (CIA) showed that the severity of arthritis was significantly lower in animals treated with the antibody (CN101456912A).