CloneID: 4B3B5
Heavy Chain modification: Fc Silent™
Antigen Long Description: The original antibody was generated by immunizing BALB/c mice with the conserved B cell epitope of filovirus Gp.
Buffer Composition: PBS only.
Chimeric Use Statement: This is a reformatted human IgG1 Fc Silent™ antibody, based on the original human IgG1 format, created for improved compatibility with existing reagents, assays and techniques.
Uniprot Accession No.: Q66810; P35253
Specificity Statement: The antibody is specific for glycoproteins (GP). In particular, it targets the epitope GAFFLYDRLAST (a.k.a peptide 1), that is conserved across all ebolavirus and marburgvirus spp glycoproteins (GP)
Application Notes (Clone): The specificity of the original format of the antibody was confirmed by ELISA analysis (Bongcam-Rudloff et al. 2023).