CloneID: Nb30
Antigen Long Description: The original antibody was isolated from a nanobody phage-display naïve library generated from the peripheral blood of non-immunized llamas. The specific antibody was isolated by panning the library against periplasmic domain of PorM protein of Porphyromonas gingivalis.
Buffer Composition: PBS with 0.02% Proclin 300.
Available Custom Conjugation Options: AP, HRP, Fluorescein, APC, PE, Biotin Type A, Biotin Type B, Streptavidin, FluoroProbes 647H, Atto488, APC/Cy7, PE/Cy7
Uniprot Accession No.: B2RLE8
Specificity Statement: This antibody binds N-terminal part comprising amino acids from 225–516 of the PorM protein of Porphyromonas gingivalis. PorM is a membrane protein that is involved in the assembly of the type IX secretion system (T9SS) in Porphyromonas gingivalis, a major bacterial pathogen that is responsible for periodontal disease in humans.
Application Notes (Clone): The binding specificity of this antibody towards C-terminal part of the PorM protein was determined using ELISA. The affinity of the antibody was found to be Kd= 4.5 ± 1.0 nM (PMID: 28471361).
English
Deutsch
