Anti-proBNP (106.3)

Anti-proBNP [106.3], Recombinant, IgG1 kappa, Human

CloneID: 106.3

Heavy Chain modification: Fc Silent™

Antigen Long Description: The original mouse antibody was generated by immunizing mice with human BNP peptide 5-13 (VQGSGAFGR) conjugated with BSA.

Buffer Composition: PBS only.

Chimeric Use Statement: This is a reformatted human IgG1 Fc Silent™ antibody, based on the original human IgG1 format, created for improved compatibility with existing reagents, assays and techniques.

Uniprot Accession No.: P16860

Specificity Statement: This antibody binds B-type natriuretic peptide (BNP) 5‐13 (VQGSGAFGR). BNP is a naturally secreted cardiac regulatory hormone that influences blood pressure and vascular water retention in human physiology. The plasma BNP concentration is a clinically recognized biomarker for various cardiovascular diseases.

Application Notes (Clone): This antibody can be used for the detection of human BNP using ELISA (PMID: 18606632). This antibody when crosslinked to POROS XL ID resin can also be used in the immunoprecipitation of BNP from plasma samples of patients with chronic heart failure (PMID: 16750161).

• SKU: ABAAb03869-10.3-BT
• Manufacturer: Absolute Antibody
• Manufacturer SKU: Ab03869-10.3-BT
• Package Unit: 1 mg
• Quantity Unit: STK
• Reactivity: Human
• Clonality: Recombinant
• Application: ELISA
• Isotype: IgG1 kappa
• Host: Human