CloneID: 2A8
Antigen Long Description: Recombinant P.vivax Pvs25.
Origin Pub PMID: 16327807
Buffer Composition: PBS with 0.02% Proclin 300.
Chimeric Use Statement: This full-length, chimeric rabbit antibody was made using the variable domain sequences of the original Mouse scFv format, for improved compatibility with existing reagents, assays and techniques.
Available Custom Conjugation Options: AP, HRP, Fluorescein, APC, PE, Biotin Type A, Biotin Type B, Streptavidin, FluoroProbes 647H, Atto488, APC/Cy7, PE/Cy7
Uniprot Accession No.: D9D8M0
Specificity Statement: The antibody binds to the 2B loop of Pvs25 with nanomolar affinity.
Application Notes (Clone): This antibody binds to Pvs25, a Plasmodium surface protein constiting of a triangular arrangement of four epidermal growth-factor-like domainst tether on the cell by a glycosylphosphatidylinositol anchor. The antibody blocks the transmission of P. vivax to mosquitoes from the blood of a P. vivax-infected chimpanzee and from the blood of patients with vivax malaria.
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