Anti-Quadruplex DNA (4E11)

Anti-Quadruplex DNA [4E11], Recombinant, IgG kappa, Rabbit
SKU
ABAAb00390-23.0
Packaging Unit
200 μg
Manufacturer
Absolute Antibody

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CloneID: 4E11

Antigen Long Description: Oxy-2 or d(TTTTGGGG)2.

Buffer Composition: PBS with 0.02% Proclin 300.

Chimeric Use Statement: This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG2a format, for improved compatibility with existing reagents, assays and techniques.

Available Custom Conjugation Options: AP, HRP, Fluorescein, APC, PE, Biotin Type A, Biotin Type B, Streptavidin, FluoroProbes 647H, Atto488, APC/Cy7, PE/Cy7

Specificity Statement: The antibody binds to quadruplex DNA with a Kd of 2.64 nM. Binds specifically to only one type of quadruplex DNA, Oxy-2 (d(TTTTGGGG)2).

Application Notes (Clone): This antibody binds to quadruplex DNA, which is generated through the association of four guanines bound through Hoogsteen base pairing. G4-forming sequences are associated with immunoglobulin switch regions, promoter sequences, rDNA and telomeric repeats.
More Information
SKU ABAAb00390-23.0
Manufacturer Absolute Antibody
Manufacturer SKU Ab00390-23.0
Package Unit 200 μg
Quantity Unit STK
Reactivity Various species
Clonality Recombinant
Application ELISA, Immunohistochemistry
Isotype IgG kappa
Host Rabbit
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