Anti-Quadruplex DNA (5E11)

Anti-Quadruplex DNA [5E11], Recombinant, IgG kappa, Goat

CloneID: 5E11

Antigen Long Description: Ver-3 or d(TGGGGG(TTAGGG)2T

Buffer Composition: PBS only.

Chimeric Use Statement: This chimeric goat antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.

Specificity Statement: The antibody binds to quadruplex DNA with a Kd of 13.1 nM. Binds to both the Ver-3 and the Oxy-2 type of quadruplex DNA.

Application Notes (Clone): This antibody binds to quadruplex DNA, which is generated through the association of four guanines bound through Hoogsteen base pairing. G4-forming sequences are associated with immunoglobulin switch regions, promoter sequences, rDNA and telomeric repeats.

• SKU: ABAAb00392-24.1-BT
• Manufacturer: Absolute Antibody
• Manufacturer SKU: Ab00392-24.1-BT
• Package Unit: 1 mg
• Quantity Unit: STK
• Reactivity: Various species
• Clonality: Recombinant
• Application: ELISA, Immunohistochemistry
• Isotype: IgG kappa
• Host: Goat