Anti-Quadruplex DNA (5E11)

Anti-Quadruplex DNA [5E11], Recombinant, IgG1 kappa, Mouse

CloneID: 5E11

Heavy Chain modification: Fc Silent™

Antigen Long Description: Ver-3 or d(TGGGGG(TTAGGG)2T

Buffer Composition: PBS with 0.02% Proclin 300.

Available Custom Conjugation Options: AP, HRP, Fluorescein, APC, PE, Biotin Type A, Biotin Type B, Streptavidin, FluoroProbes 647H, Atto488, APC/Cy7, PE/Cy7

Specificity Statement: The antibody binds to quadruplex DNA with a Kd of 13.1 nM. Binds to both the Ver-3 and the Oxy-2 type of quadruplex DNA.

Application Notes (Clone): This antibody binds to quadruplex DNA, which is generated through the association of four guanines bound through Hoogsteen base pairing. G4-forming sequences are associated with immunoglobulin switch regions, promoter sequences, rDNA and telomeric repeats.

• SKU: ABAAb00392-1.4
• Manufacturer: Absolute Antibody
• Manufacturer SKU: Ab00392-1.4
• Package Unit: 200 μg
• Quantity Unit: STK
• Reactivity: Various species
• Clonality: Recombinant
• Application: ELISA, Immunohistochemistry
• Isotype: IgG1 kappa
• Host: Mouse