Anti-Quadruplex DNA (8H2)

Anti-Quadruplex DNA [8H2], Recombinant, IgG kappa, Rabbit

CloneID: 8H2

Antigen Long Description: Ver-3 or d(TGGGGG(TTAGGG)2T.

Buffer Composition: PBS only.

Chimeric Use Statement: This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG2b format, for improved compatibility with existing reagents, assays and techniques.

Specificity Statement: The antibody binds to quadruplex DNA with a Kd of 7.22 nM. Binds specifically to the Ver-3 tpye of quadruplex DNA.

Application Notes (Clone): This antibody binds to quadruplex DNA, which is generated through the association of four guanines bound through Hoogsteen base pairing. G4-forming sequences are associated with immunoglobulin switch regions, promoter sequences, rDNA and telomeric repeats.

• SKU: ABAAb00391-23.0-BT
• Manufacturer: Absolute Antibody
• Manufacturer SKU: Ab00391-23.0-BT
• Package Unit: 1 mg
• Quantity Unit: STK
• Reactivity: Various species
• Clonality: Recombinant
• Application: ELISA, Immunohistochemistry
• Isotype: IgG kappa
• Host: Rabbit