Anti-RNase A (cAb-RN05)

Anti-RNase A [cAb-RN05], Recombinant, IgG1-Fc Fusion, Mouse

CloneID: cAb-RN05

Antigen Long Description: The original antibody was generated by immunizing a dromedary (Camelus dromedarius) with bovine RNase A. The affinity matured version of this antibody was generated using synthetic combinatorial libraries.

Buffer Composition: PBS only.

Uniprot Accession No.: P61823

Specificity Statement: This antibody binds bovine RNase A. RNase A is an endonuclease enzyme that catalyzes the cleavage of RNA on the 3' side of pyrimidine nucleotides. It acts on single-stranded and double-stranded RNA.

Application Notes (Clone): This antibody binds bovine RNase with an affinity in the picomolar range. This affinity matured version of VHH antibody cAb-RN05 binds bovine RNase with an affinity of Kd= 180 pM (PMID: 17888451). 5′–3′ cUMP that binds into the active site of RNase A does not compete with cAb-RN05 for binding to RNase A in an ELISA (PMID: 10196124).

• SKU: ABAAb03287-1.159-BT
• Manufacturer: Absolute Antibody
• Manufacturer SKU: Ab03287-1.159-BT
• Package Unit: 500 μg
• Quantity Unit: STK
• Reactivity: Cow (Bovine)
• Clonality: Recombinant
• Application: ELISA
• Isotype: IgG1-Fc Fusion
• Host: Mouse