Anti-ROR1 (1G8)

Anti-ROR1 [1G8], Recombinant, IgG1 kappa, Human

CloneID: 1G8

Antigen Long Description: A human antibody library generated from the peripheral blood lymphocytes of human donors. This specific clone was isolated by panning the library against human ROR1 protein.

Buffer Composition: PBS only.

Uniprot Accession No.: Q01973

Specificity Statement: This antibody binds the human ROR1. ROR1 is a type I membrane protein and belongs to the ROR subfamily of cell surface receptors. It is a pseudo kinase that lacks catalytic activity. Receptor tyrosine kinase ROR1 plays an essential role in embryogenesis and is overexpressed in many types of malignant tumors. Antibody-based immunotherapies targeting ROR1 have been developed and evaluated in preclinical and clinical studies with promising outcomes.

Application Notes (Clone): The original human IgG1 version of this antibody binds human ROR1 protein with a binding affinity of Kd= 4.9 nM. This antibody can be used for the detection of human ROR1 using flow cytometry (CN104817642).

• SKU: ABAAb03865-10.0-BT
• Manufacturer: Absolute Antibody
• Manufacturer SKU: Ab03865-10.0-BT
• Package Unit: 1 mg
• Quantity Unit: STK
• Reactivity: Human
• Clonality: Recombinant
• Application: Flow Cytometry
• Isotype: IgG1 kappa
• Host: Human