Anti-SOD1 (591-37-M1)

Anti-SOD1 [591-37-M1], Recombinant, IgG kappa, Rabbit

CloneID: 591-37-M1

Antigen Long Description: The original antibody was raised by immunizing mice with Trx-bhSOD1-A4V.

Buffer Composition: PBS with 0.02% Proclin 300.

Available Custom Conjugation Options: AP, HRP, Fluorescein, APC, PE, Biotin Type A, Biotin Type B, Streptavidin, FluoroProbes 647H, Atto488, APC/Cy7, PE/Cy7

Specificity Statement: This antibody is specific for misfolded SOD1.

Application Notes (Clone): This antibody was used for an ELISA on b-hSOD1, b-hSOD1-A4V, b-hSOD1-G85R and b-hSOD1-G93A. This antibody was used for immunoprecipitation on HEK-293T cells transfected with mutated human SOD1. The antibody was used for immunofluorescence on HEK-293T cells transiently transfected with hSOD1-G93A. The antibody was also used for immunohistochemistry on tissue from a mouse model of ALS, and on spinal cords of sporadic ALS patients, the mice expressed either hSOD1 or hSOD1-G93A. This antibody was used in vivo on mouse ALS models. It showed that the mice treated with the antibody maintained better weight and extended life (US9663586B2).

• SKU: ABAAb04674-23.0
• Manufacturer: Absolute Antibody
• Manufacturer SKU: Ab04674-23.0
• Package Unit: 100 μg
• Quantity Unit: STK
• Reactivity: Human
• Clonality: Recombinant
• Application: Immunoprecipitation, ELISA, Flow Cytometry, Immunohistochemistry, In Vivo Assay
• Isotype: IgG kappa
• Host: Rabbit