CloneID: 77 Fab
Heavy Chain modification: Fc Silent™
Antigen Long Description: Testosterone.
Buffer Composition: PBS only.
Chimeric Use Statement: This chimeric human antibody was made using the variable domain sequences of the original Mouse Fab format, for improved compatibility with existing reagents, assays and techniques.
Specificity Statement: This antibody is specific for testosterone, a steroid hormone secreted by the testicles that acts as the principle male sex hormone and anabolic steroid.
Application Notes (Clone): This antibody binds to The original version of this antibody (mouse Fab) was shown to bind testosterone with a Kd of 0.3 nM and an ED50 of 4.8 nM (Valjakka et al., 2002; PMID: 12196551). The binding mechanism of this antibody was explored via crystallography (Niemi et al., 2011; 21360611).