CloneID: anti-TDRKH-RAB-C143
Heavy Chain modification: Fc Silent™
Antigen Long Description: The original antibody was raised by panning against a phage-display library using recombinant TDRD2 eTudor.
Buffer Composition: PBS only.
Chimeric Use Statement: This is a reformatted human IgG1 Fc Silent™ antibody, based on the original human Fab format, created for improved compatibility with existing reagents, assays and techniques.
Uniprot Accession No.: Q9Y2W6
Specificity Statement: This antibody is specific for human Tudor and KH domain-containing protein.
Application Notes (Clone): The original antibody was used for an ELISA on recombinant TDRD2 eTudor. The structure of the original antibody was determined using x-ray crystallography. This antibody was used for a pull-down assay on TDRD2 eTudor domain (Chen et al., 2020; PMID:31288074). This antibody was used for immunofluorescence on different human cell lines. This antibody showed staining of the cytoplasm for all cell lines tested (Hornsby et al., 2015; PMID:26290498).
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