Anti-Urokinase-type plasminogen activator (mAb-112)

Anti-Urokinase-type plasminogen activator [mAb-112], Recombinant, F(ab)2 kappa, Human

CloneID: mAb-112

Heavy Chain modification: AbFab2™ His-Tagged

Antigen Long Description: Human recombinant single chain pro-uPA.

Origin Pub PMID: 19047064

Buffer Composition: PBS with 0.02% Proclin 300.

Chimeric Use Statement: This chimeric human antibody was made using the variable domain sequences of the original mouse IgG1 format for improved compatibility with existing reagents, assays and techniques.

Available Custom Conjugation Options: AP, HRP, Fluorescein, APC, PE, Biotin Type A, Biotin Type B, Streptavidin, FluoroProbes 647H, Atto488, APC/Cy7, PE/Cy7

Uniprot Accession No.: P00748

Specificity Statement: The antibody binds to pro-uPA with a Kd of 0.8E-9M.

Application Notes (Clone): The antibody binds to and stabilizes pro-uPA, the zymogen form (inactive) of urokinase-type plasminogen activator. Active uPA catalyzes the conversion of plasminogen to the active protease plasmin, a protease that degrades extracellular matrix proteins. T

• SKU: ABAAb00367-10.7
• Manufacturer: Absolute Antibody
• Manufacturer SKU: Ab00367-10.7
• Package Unit: 200 μg
• Quantity Unit: STK
• Reactivity: Human
• Clonality: Recombinant
• Application: Western Blotting, Blocking
• Isotype: F(ab)2 kappa
• Host: Human